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Table 2 Description of selected studies

From: A systematic review of the application and utility of geographical information systems for exploring disease-disease relationships in paediatric global health research: the case of anaemia and malaria

 Author (year)

 Source

Objectives

Target population

Target outcome(s)

Reporting quality (% score)

Quality of evidence (rating)

Snow (1999b) [30]

Bull World Hlth Org

Estimate age-structured rates of the fatal, morbid and disabling sequelae following expoure to malaria infection under different epiemiolgical conditions.

African population

Malaria

86.67

0

MARA/ARMA (1998) [31]

MARA website

Provide a continental perspective of where, how much, when, why, and who is affected by malaria, and establish a continental database of the spatial distribution of malaria in Africa

children < 10y (excluding infants) in Africa

Malaria

85.00

0

Snow (1998a) [32]

Trans Roy Soc Trop Med Hyg

Develop climate-based model of transmission intensity and estimate annual morbidity and mortality burden of malaria among children in Kenya.

Children 0-10y in Kenya

Malaria

83.87

−1

Schellenberg et al., (1998) [26]

Int Epi Assoc

Study the geographicla pattern of hospital admissions for severe malaria and stability of this pattern over time in Kilifi Distric, Kenya.

Children < 5y in Kenya

Malaria

81.25

1

Giardina et al. (2012) [28]

PloS One

Provide spatially explicit burden estimates of malaria using survey data and Bayesian geostatistical zero-inflated binomial models.

Children 6–59 months in Senegal

Malaria

78.13

2

WHO (2010) [33]

WHO website

Document success in reducing global malaria burden by summarizing information received from 160 malaria-endemic countries/areas and updating analyses presented in previous annual report.

All population groups with malaria data reported to WHO.

Malaria

77.59

−1

Root (1999) [34]

Int J Pop Geog

Map and describe distribution of under-five mortality at provincial level and examine degree to which socio-economic factors and regional disease environments are responsible for spatial patterns.

Children < 5y in 20 sub-Saharan African countries

Malaria

74.19

−1

Snow (1999a) [35]

Parasitology Today

Define spatial limits of populations exposed to risk of malaria infection in Africa and obtain best estimate of malaria attributable mortality among infants and children.

Children 0-4y in Africa

Malaria

72.41

−1

WHO (2008b) [7]

WHO website

Rreview progress in controlling malaria burden, implementing national policies and strategies on malaria control, funding to support malaria control, and evidence generation on the epidemiological impact of malaria control programmes.

All population groups with malaria data reported to WHO.

Malaria

70.69

−1

Hightower et al., (1998) [27]

Am J Trop Med Hyg

Illustrate usefulness of Differential Geographical Positioning System (DGPS) maps to produce a highly accurate base map in a tropical area.

Children < 5 years in Siaya district, Western Kenya

Malaria

69.35

1

Mbogo (1995) [36]

Am J Trop Med Hyg

Evaluate the transmission of P. falciparumby vector populations relative to the incidence of severe malaria infections.

Children 0-4y from nine sites in Kenya

Malaria

62.50

−1

Mbogo (1993) [25]

Am J Trop Med Hyg

Examine dynamics of P. falciparum transmission by vector populations in relation to the incidenc of severe malaria infections.

Children 1-4y from two study sites in Kilifi District, Kenya

Malaria

61.29

1

Anthony et al., (1992) [37]

Am J Trop Med Hyg

Report findings of a 15-month malaria investigation and identify factors contributing to its origin, exacerbation and persistence.

Children 0-4y in remote highland community of Oksibil, Indonesia

Malaria

59.86

0

Gordon (2004) [38]

WHO website

Describe environmental factors that affect child health (including parasitic infections such as malaria).

Children < 5y worldwide

Malaria

41.38

0

WHO (2008a) WHO [2]

WHO website

Collect and present information on anaemia prevalence by country and WHO region.

All population groups [Children 0.5-4.99y, 5–14.99y, (non) pregnant women, men, elderly]

Anaemia

88.33

−1

Magalhaes (2011) [24]

PLoS Medicine

Estimate the geographical risk profile of anaemia while accounting for malaria, malnutrition, and helminth infections. Estimate the risk of anaemia attributable to these factors, and the number of anaemia cases in preschool-aged children for 2011.

Children 1-4y in Burkina Faso, Ghana, and Mali

Anaemia

87.50

1

Greenwell (2006) [29]

Population Association America

Examine the utility of using child hemoglobin measures (collected in population-based studies) as an indicator for monitoring malaria morbidity.

Children 6–59 months in five sub-Saharan African countries

Anaemia / Malaria

84.38

2

Mainardi (2012) [21]

Int J Geo Info Sci

Re-assess spatial heterogeneity and anisotropy of moderate and severe anaemia using variograms and geographically weighted regression (GWR) models.

Children < 5y in 173 regions of 20 sub-saharan African countries.

Anaemia

76.67

2

Snow (1994) [22]

Acta Topica

Describe and quantify clinical burden of malaria in communities with markedly different levels of P. falciparum transmission in East Africa.

Children 0-9y in Kilifi, Kenya and Ifakara, Tanzania

Anaemia / Malaria

70.97

−1

Tanzanian NBS and ICF International (2012) [39]

MEASURE DHS website

Summarize findings of the 2010 Tanzanian DHS, and provide an atlas of maps intended to easily communicate regional differences in maternal and child health.

Women (15-49y) and children (6-59 m) in Tanzania

Anaemia

66.67

0